ALL >> General >> View Article
Brittle Bone Disease Information

Brittle bone disease is usually caused by a genetic factor that affects the formation and production of type 1 collagen, the protein that is used to create bone. This defective gene is inherited but the defect may also occur as a result of a spontaneous mutation. There are some forms of the disease that may be fatal to babies before or even immediately after birth.
Types
There are 4 genes that are responsible for the production of collagen and one or all of them may be affected. The combination causes 8 different types of brittle bone disease that are usually named from 1 01 up to 8 01. The most common types are usually the first 4 while the last 4 are extremely rare with most of them being type 4 01 subtypes.
Type 1 01 is the most common but mildest form of the disease in babies. The body of the child produces the normal quality collagen but it doesn’t produce enough of it resulting in bones that are only mildly fragile. Babies with this form can suffer from bone fractures as a result of mild traumas. They may also experience dental cavities and cracks as teeth ...
... are also affected. Type 2 01 is usually the most severe type of the disease and can be fatal. This form of the diseases causes the body of the child to produce collagen that is either not enough or of poor quality causing bone deformities. Babies born with this form of the brittle bone disease suffer from misshapen or broken ribs, narrowed chests as well as lungs that are undeveloped. Infants with this disease will either die in the womb or even shortly after birth.
Type 3 01 is also a severe form of the disease that may cause the bones to break easily. This forms of the disease causes the baby’s body to produce enough collagen but of poor quality. The bones of the baby may even start breaking before birth. The disease causes bone deformities and the condition may worsen as the child grows. Type 4 01 has symptoms ranging from mild to severe. This form of the disease causes the body to produce enough collagen but of poor quality. Babies born with type 4 01 usually have bowed legs but the bowing will lessen with age.
Treatment
Brittle bone disease has no cure but there are therapy and equipment options that can help to correct some symptoms. You can donate to help prevent and correct fractures. Through your donations patients suffering from the disease can access wheelchairs, braces, physical therapy and extensive dental and surgical procedures. You can also donate towards the rodding cost or even other surgical procedures that can be used to prevent any subsequent fractures.
Add Comment
General Articles
1. The Role Of Empathy, Collaboration, Intuition, And Judgment In An Ai-driven WorldAuthor: Indu kumari
2. Caring For Your Rolex Gold Watch: Maintenance Tips
Author: The Diamond Box
3. Nfl London: Eagles Trade For Qb Sam Howell From Vikings
Author: eticketing.co
4. High-paying Jobs You Can Get With A Diploma Of Building And Construction
Author: marish
5. Nfl London: The Aaron Rodgers Era Ends In New York
Author: eticketing.co
6. Asia Cup: Fans Promised World-class Cricket In Neutral Venues
Author: eteckiting.co
7. Choosing The Right Floor Polishing Service For Your Needs
Author: Prestige
8. Why Businesses Choose Zoetic Bpo Services For Offline Bpo Projects?
Author: simon
9. Top Reasons A Consulting Firm Is Ideal For Esg Compliance In The Uae Market
Author: sweta
10. Nfl London: Browns Move On From Diontae Johnson
Author: eticketing.co
11. Cheap Smm Panel – The Smart Way To Grow Social Media
Author: Indianvipsmm
12. Book Keeping And Accounting Services: The Unsung Backbone Of Scalable Businesses
Author: DGA Global
13. Cubic Zirconia Necklace Set – Sparkling Elegance For Every Occasion
Author: pittijewelsandpearls
14. Look For The Best Dentist In Virar
Author: pravindentalclinic
15. Wisdom Teeth Removal Adelaide – Everything You Should Know
Author: Armita Karn