Glutathione Clinical References-heavy Metal Toxicity, Hiv, Huntington’s Disease

By Author: Robert Price
Total Articles: 4
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Glutathione is the mother of all anti-oxidants that is essential for healthy and disease free living. Max Health Labs offers Liposomal Vitamin B12 and Intracellular Vitamin B12 supplements that provide us the benefits of this super anti-oxidant.

Heavy Metal Toxicity

Metals, Toxicity and Oxidative Stress. (1)

The role of transport in chemical nephrotoxicity. (2)

Oxidative mechanisms in the toxicity of metal ions. (3)

The distribution of total mercury in the brain after the lateral ventricular single injection of methyl mercury and glutathione. (4)

Chromosome-damaging activity of ferritin and its relation to chelation and reduction of iron. (5)

Molecular Interactions with Mercury in the Kidney. (6)

Cellular resistance to methyl mercury. (7)

Glutathione depletion and in vitro lipid peroxidation in mercury or maleate induced acute renal failure. (8)

Mercury toxicity and antioxidants: Part I: Role of glutathione and alpha-lipoic acid in the treatment of mercury toxicity. (9)

HIV

Glutathione metabolism and its ...
... implications for health. (10)

Disturbed glutathione metabolism and decreased antioxidant levels in human immunodeficiency virus–infected patients during highly active antiretroviral therapy—potential immunomodulatory effects of antioxidants. (11)

Oxidative metabolism of HIV-infected macrophages: the role of glutathione and a pharmacologic approach. (12)

Protective effect of glutathione in HIV-1 lytic peptide 1-induced cell death in human neuronal cells. (13)

Increased erythrocyte glutathione peroxidase activity and serum tumor necrosis factor-alpha in HIV-infected patients. (14)

HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells. (15)

Protein glutathionylation: Coupling and uncoupling of glutathione to protein thiol groups in lymphocytes under oxidative stress and HIV infection. (16)

N-acetylcysteine replenishes glutathione in HIV infection. (17)

Regional differences in emphysema scores and BAL glutathione levels in HIV-infected individuals. (18)

Quantitation of reduced glutathione and cysteine in human immunodeficiency virus-infected patients. (19)

Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction. (20)

The importance of glutathione in human disease. (21)

Glutathione deficiency is associated with impaired survival in HIV disease. (22)

Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration. (23)

Huntington's Disease

Increased glutathione levels in cortical and striatal mitochondria of the R6/2 Huntington's disease mouse model. (24)

References:

(1)Current Medicinal Chemistry. 2005; 12: 1161-1208.

(2)ToxicolPathol. 1998 Jan-Feb; 26(1):52-7.

(3)Free RadicBiol Med. 1995 Feb; 18(2):321-36.

(4)Res CommunChemPatholPharmacol. 1988 Apr; 60(1):57-69.

(5)Cancer Research 1981 May; 41:1628-1636.

(6)Am Soc for Pharm and ExpTher. 2008; Vol. 52, No. 1; pp.113-139.

(7)Neurotoxicology. 1996 Spring; 17(1):27-36.

(8)BiochemPharmacol. 1983 Oct 1; 32(19):2969-72.

(9)Alternative Medicine Review, Dec, 2002.

(10)J. Nutr. 2004; 134: 489–492.

(11)The Journal of Infectious Diseases 2003; 188:232–8.

(12)PatholBiol (Paris). 2001 Sep; 49(7):567-71.

(13)J Neurovirol. 2001 Oct; 7(5):454-65.

(14)Relationship to on-going prothrombotic state J Hematother Stem Cell Res. 2002 Apr;11(2):369-75

(15)Brain Res. 2005 May 31; 1045(1-2):57-63. Epub 2005 Apr 19.

(16)Molecular Immunology. 2001; 38: 773–780.

(17)European Journal of Clinical Investigation 2000; 30:915-929.

(18)Chest 2004; 126:1439-1442.

(19)Electrophoresis. 2004 Jun;25(10-11):1522-9

(20)FASEBJ. 1997; 11:1077-1089.

(21)Biomed Pharmacother. 2003 May-Jun; 57(3-4):145-55.

(22)ProcNatlAcad Sci. USA Vol. 94, pp1967–1972, March 1997.

(23)Am J Physiol Heart Circ Physiol. 2008 June ; 294(6): H2792–H2804

(24)NeurosciLett. 2005 Sep 23; 386(1):63-8.

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