Various Views Of Stem Cell

By Author: sudarshan singh
Total Articles: 327
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Tissue regeneration is probably the most important possible application of stem cell research.Organs must be donated and transplanted but the demand for organs far exceeds supply.Stem cells could potentially be used to grow a particular type of tissue or organ if directed to differentiate in a certain way.Stem cells differentiate when they leave that niche or no longer receive those signals.The signals that lead to reprogramming of cells to an embryonic-like state are also being investigated. These signal pathways include several transcription factors including the oncogene c-Myc. Initial studies indicate that transformation of mice cells with a combination of these anti-differentiation signals can reverse differentiation and may allow adult cells to become pluripotent.The need to transform these cells with an oncogene may prevent the use of this approach in therapy. An extremely rich source for adult mesenchymal stem cells is the developing tooth bud of the mandibular third molar.The stem cells eventually form enamel, dentin, periodontal ligament, blood vessels, dental pulp, nervous tissues and a minimum of 29 different end ...
... organs. Because of extreme ease in collection at 8–10 years of age before calcification and minimal to no morbidity, these will probably constitute a major source of cells for personal banking, research and current or future therapies.These stem cells have been shown capable of producing hepatocytes.Stem cells have an important benefit for the pharmaceutical field. New drugs can be tested on stem cells to assess their safety before testing drugs on animal and human models. Stem cells offer hope for effective treatment or perhaps even a reversal of the disease. Time will confirm the full success of stem cell therapies and continued research should teach us more about using stem cells to treat debilitating medical conditions.

Current medical research is focused on two particular types of stem cells - adult and embryonic. Out of the three types, two are able to develop into any type of cell within the human body. These two are called totipotent and pluripotent respectively. Stem cells that are pluripotent have the capability of forming virtually all the possible tissue types found in human beings. These cells can only be found in a particular stage in human embryos. Multipotent cells are partially differentiated so that they can form a restricted number of tissue types. Multipotent stem cells can be found in the fetus, in numerous adult tissues and umbilical cord blood. The third type of stem cells have less regeneration potential and can only develop into a limited number of other types of cells.cord blood stem cells have a high rate of engraftment are more tolerant of HLA mismatches result in a reduced rate of graft-versus-host disease and are rarely contaminated with latent viruses which simply means that the body often accepts cord blood stem cells better than those from bone marrow.Banked cord blood stem cells are readily accessible, allowing treatment to begin earlier if required, with no time wasted in the search and matching process required for publicly banked stem cells.Stem cells have enormous potential in health and medical research but to fully harness this potential, scientists are studying how stem cells transform, or differentiate, into the diverse range of specialised cells.Stem cells offer a viable source of replacement cells to treat diseases and can potentially reduce the morbidity and mortality for those awaiting transplants.Burn victims tend to endure an enormous amount of pain from their wounds as well as frustration from the challenges of healing.

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