1-[2-(2-hydroxyethoxy)ethyl] Piperazine (cas 40018-26-6) – Pharma Intermediate For Quetiapine Fumarate Api | Valeshvar Biotech

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In the pharmaceutical industry, high-purity intermediates play a critical role in producing safe and effective medicines. One such important intermediate is 1-[2-(2-Hydroxyethoxy)ethyl] piperazine (CAS №40018–26–6), widely used in the synthesis of Quetiapine Fumarate API, an active pharmaceutical ingredient used in antipsychotic medications.

Valeshvar Biotech is a trusted manufacturer and supplier of high-quality pharmaceutical intermediates, offering consistent purity, reliable supply, and industry-compliant production standards.

What is 1-[2-(2-Hydroxyethoxy)ethyl] Piperazine?
1-[2-(2-Hydroxyethoxy)ethyl] piperazine is an organic compound belonging to the piperazine derivative family, commonly used as a pharmaceutical intermediate. Intermediates are chemicals used in the early stages of drug synthesis before the final active pharmaceutical ingredient (API) is formed.

This compound is also known by the chemical name:

2-[2-(Piperazin-1-yl)ethoxy] ethan-1-ol
CAS No: 40018–26–6
...
... Due to its stable structure and reactive functional groups, it is widely used in the production of central nervous system (CNS) drugs, especially Quetiapine Fumarate.

Product Details — Technical Specification
PropertyDetailsProduct Name1-[2-(2-Hydroxyethoxy)ethyl] PiperazineOther Name2-[2-(Piperazin-1-yl)ethoxy] ethan-1-olCAS Number40018–26–6Chemical FormulaC8H18N2O2Molecular Weight174.24CategoryPharmaceutical IntermediateEnd UseQuetiapine Fumarate APIManufacturerValeshvar BiotechIndustryPharma / API Manufacturing

Importance of Pharmaceutical Intermediates in API Manufacturing
In pharmaceutical production, drugs are not made in a single step. Instead, they are created through multiple chemical reactions.
During this process, intermediate compounds like 1-[2-(2-Hydroxyethoxy)ethyl] piperazine are used to build the final molecule.

Pharmaceutical intermediates must have:

High purity
Stable chemical structure
Controlled impurities
Consistent batch quality
Compliance with pharma standards
Without high-quality intermediates, it becomes impossible to manufacture safe and effective APIs.

Role in Quetiapine Fumarate API Production
Quetiapine Fumarate is an antipsychotic drug used for treating:

Schizophrenia
Bipolar disorder
Major depressive disorder (in some cases)
To produce this API, manufacturers require specific intermediates, and
1-[2-(2-Hydroxyethoxy)ethyl] piperazine is one of the key building blocks in the synthesis process.

Why this intermediate is important
Provides the required piperazine structure
Helps in forming the side chain of Quetiapine
Ensures correct molecular configuration
Supports high-yield API production
Because of this, pharma companies require reliable suppliers like Valeshvar Biotech.

Why Choose Valeshvar Biotech for Pharma Intermediates
Valeshvar Biotech is known for manufacturing high-quality pharmaceutical intermediates with strict quality control and consistent supply.

Key advantages
High purity chemical production
Advanced manufacturing facility
Batch consistency
Competitive pricing
Reliable delivery
Suitable for API manufacturers
Custom quantity supply available
The company focuses on producing API-grade intermediates suitable for regulated and non-regulated markets.

Chemical Properties of 1-[2-(2-Hydroxyethoxy)ethyl] Piperazine
This compound contains both piperazine ring and ethoxy alcohol group, making it highly useful for organic synthesis.

Important chemical features
Contains nitrogen atoms for reactivity
Alcohol group for further reaction
Stable at room temperature
Soluble in common organic solvents
Suitable for multi-step synthesis
These properties make it ideal for pharmaceutical research and industrial drug manufacturing.

Applications in Pharmaceutical Industry
The primary application of
1-[2-(2-Hydroxyethoxy)ethyl] piperazine (CAS 40018–26–6) is in the pharma sector, but its chemical structure allows use in different synthesis processes.

Main applications
Quetiapine Fumarate API synthesis
CNS drug intermediates
Research chemicals
Bulk drug manufacturing
Contract manufacturing projects
Because of its versatility, it is a high-demand intermediate in API production.

Quality Standards Followed by Valeshvar Biotech
For pharmaceutical intermediates, quality is extremely important.

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Valeshvar Biotech follows strict procedures such as:

Controlled raw material sourcing
Batch testing
Purity verification
Chemical analysis
Proper packaging
Safe storage
This ensures the product is suitable for pharmaceutical manufacturing use.

Packaging and Supply Options
Valeshvar Biotech provides flexible packaging options depending on customer requirements.

Typical packaging includes:

HDPE drums
Fiber drums
Custom packing
Bulk supply
Safe packaging ensures that the material remains stable during transportation.

Global Demand for Quetiapine Intermediate
With the increasing demand for antipsychotic medicines, the demand for intermediates like
CAS 40018–26–6 is also growing.

Pharmaceutical companies across:

India
Europe
USA
China
Middle East
require reliable suppliers for Quetiapine API intermediates.

This makes manufacturers like Valeshvar Biotech important partners in the global pharma supply chain.

1-[2-(2-Hydroxyethoxy)ethyl] piperazine (CAS №40018–26–6) is an important pharmaceutical intermediate used in the production of Quetiapine Fumarate API. With its stable structure and high reactivity, it plays a key role in modern drug manufacturing.

Valeshvar Biotech provides high-quality intermediates with reliable purity, consistent supply, and industry-level standards, making it a trusted partner for pharmaceutical manufacturers worldwide.

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