Cas No 137862-53-4 (valsartan)

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Everything You Need to Know About Valsartan (CAS NO: 137862-53-4)
Valsartan is a widely prescribed medication used to treat high blood pressure (hypertension) and heart failure. As a member of the angiotensin II receptor antagonists (ARBs) class of drugs, valsartan works by blocking the action of a hormone known as angiotensin II, which causes blood vessels to constrict. By blocking this hormone, valsartan helps relax and widen blood vessels, making it easier for the heart to pump blood and reducing blood pressure.
In this blog post, we will explore the chemical nature, uses, mechanism of action, side effects, and safety precautions related to valsartan, identified by its CAS number 137862-53-4.

What is Valsartan?
Valsartan is an oral medication that belongs to the class of angiotensin II receptor antagonists (ARBs). These drugs are used primarily to treat conditions related to high blood pressure and heart failure. Valsartan is also prescribed to reduce the risk of death after a heart attack, as well as to improve the heart's function in patients with certain heart conditions.
Its molecular formula ...
... is C24H29N5O3, and its CAS number is 137862-53-4. The drug is typically taken in tablet form and can be prescribed alone or in combination with other medications depending on the condition being treated.
How Does Valsartan Work?
Valsartan works by blocking the action of angiotensin II, a powerful vasoconstrictor in the body. Angiotensin II plays a critical role in regulating blood pressure by causing blood vessels to constrict. When valsartan blocks the receptors that normally interact with this hormone (angiotensin II type 1 receptors), blood vessels relax, leading to a decrease in blood pressure.
By lowering blood pressure, valsartan helps prevent strokes, heart attacks, and kidney damage caused by high blood pressure. It also reduces the workload on the heart, which is especially beneficial in patients with heart failure.
Medical Uses of Valsartan
Valsartan is primarily prescribed for the following conditions:
Hypertension (High Blood Pressure): Valsartan is often used to treat hypertension, either alone or in combination with other antihypertensive agents. By lowering blood pressure, it helps prevent long-term damage to vital organs, including the heart and kidneys.
Heart Failure: In patients with heart failure, valsartan helps reduce the strain on the heart, improving its efficiency in pumping blood and preventing further damage to the heart muscle.
Post-Heart Attack (Myocardial Infarction): Valsartan can be used in post-myocardial infarction patients to improve recovery and reduce the risk of death.
Chronic Kidney Disease (CKD): For people with chronic kidney disease, valsartan may be used to protect kidney function, particularly when kidney disease is associated with hypertension or diabetes.
Side Effects of Valsartan
Like all medications, valsartan can cause side effects, although not everyone will experience them. Some of the common and serious side effects include:
Common Side Effects:
Dizziness or lightheadedness, especially when standing up quickly
Fatigue
Headache
Nausea
Serious Side Effects:
Low blood pressure (hypotension), especially after the first dose
Elevated potassium levels (hyperkalemia), which can cause irregular heart rhythms
Kidney dysfunction, which can be detected through blood tests
Angioedema (swelling of the face, lips, throat, or tongue), which can be life-threatening in rare cases
Liver problems, including jaundice and elevated liver enzymes
If you experience any severe allergic reactions or symptoms like swelling in the throat, it is important to seek immediate medical attention.
Safety Precautions and Considerations
Kidney and Liver Function: People with pre-existing kidney or liver conditions should take valsartan with caution. Kidney function should be monitored periodically through blood tests to ensure proper function while on this medication.
Pregnancy and Breastfeeding: Valsartan is contraindicated during pregnancy, particularly in the second and third trimesters, as it can harm the developing fetus. It should not be used while breastfeeding unless absolutely necessary.
Drug Interactions: Valsartan can interact with other medications, including other blood pressure-lowering drugs, potassium supplements, and certain pain relievers. It's important to inform your doctor of all medications you are currently taking to avoid any adverse interactions.
Electrolyte Imbalance: Because valsartan can increase potassium levels in the blood, potassium levels should be monitored regularly, particularly in individuals who are taking potassium-sparing diuretics or potassium supplements.
Dosage and Administration
Valsartan is available in various strengths, typically ranging from 40 mg to 320 mg. The dosage will depend on the individual's medical condition, response to treatment, and whether other medications are being taken alongside it. The medication is usually taken once daily, with or without food, but should always be taken as prescribed by a healthcare provider.
Patients should not suddenly stop taking valsartan without consulting a doctor, as this can lead to a sudden increase in blood pressure or worsening of heart failure.
Conclusion
Valsartan (CAS NO: 137862-53-4) is an essential drug used in the management of hypertension, heart failure, and other cardiovascular conditions. By blocking the action of angiotensin II, it helps reduce blood pressure and decrease the workload on the heart, improving long-term health outcomes for patients. As with all medications, it is important to follow the prescribed dosage, monitor for potential side effects, and consult a healthcare provider if any issues arise.
If you are prescribed valsartan, be sure to keep regular appointments with your healthcare provider to monitor your blood pressure, kidney function, and overall health while on this medication.
URL: For more information, visit Synnat Pharma : CAS NO 137862-53-4 (VALSARTAN)