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Understanding CAS No. 35180-01-9: A Comprehensive Guide
CAS numbers are unique identifiers used to track chemical compounds with precision. They help researchers, manufacturers, and regulatory agencies identify substances across various industries and applications. CAS No. 35180-01-9 is tied to a compound called N-ethyl-2-pyrrolidone (NEP), an organic chemical compound that may not be as widely recognized as others but still plays a crucial role in several industries. This guide explores the nature, applications, and safety considerations of NEP, shedding light on its importance.

What Is N-Ethyl-2-Pyrrolidone (NEP)?
N-ethyl-2-pyrrolidone (NEP) is an organic solvent that belongs to a group of chemicals called pyrrolidones. These are characterized by a five-membered lactam ring structure, which is a cyclic amide. NEP is commonly used in various industries because of its ability to dissolve both hydrophobic (water-repelling) and hydrophilic (water-attracting) substances. This makes it highly versatile in a wide range of applications.
NEP is typically a colorless to pale yellow liquid with a slightly amine-like ...
... odor. Its molecular formula is C6H11NO, and it has a molecular weight of 113.16 g/mol. The compound has a boiling point of 204°C and a melting point of -24°C, which gives it a broad range of applications under different temperature conditions.
Key Chemical Properties of NEP
Appearance: Colorless to pale yellow liquid with a faint, amine-like smell.
Molecular Formula: C6H11NO.
Molecular Weight: 113.16 g/mol.
Boiling Point: 204°C.
Melting Point: -24°C.
Solubility: NEP is highly soluble in water and many organic solvents, which makes it a useful solvent for various chemical processes.
Major Applications of N-Ethyl-2-Pyrrolidone (NEP)
NEP is widely used in different industries due to its unique solvent properties, which allow it to dissolve a broad range of substances. Some of the primary applications of NEP are in chemical synthesis, pharmaceuticals, electronics, and agriculture.
1. Chemical Synthesis and Manufacturing
NEP plays an important role in the chemical synthesis of many products. It is often used as a solvent in chemical reactions, including polymerization (the process of creating polymers). Additionally, NEP is found in the production of paints, coatings, adhesives, and other chemical formulations. Its ability to dissolve both water-soluble and water-insoluble compounds makes it an excellent solvent in processes that require a combination of different chemicals. It aids in the creation of high-performance materials used in everything from coatings on cars to adhesives in electronics.
2. Pharmaceuticals and Biotechnology
In the pharmaceutical and biotechnology industries, NEP is used as a solvent to help dissolve active pharmaceutical ingredients (APIs) in the creation of medications. The solubility properties of NEP are critical to improving the stability of drugs and ensuring they can be delivered efficiently into the body. NEP helps improve the bioavailability of drugs, meaning it can enhance the absorption and distribution of medications in the bloodstream, leading to more effective treatments.
NEP is also used in drug delivery systems, such as injectable formulations and transdermal patches, where it ensures that the active ingredients remain stable and effective for a longer period. Its versatility is particularly useful when formulating medications that need to be absorbed through different methods, whether orally, intravenously, or through the skin.
3. Electronics and Battery Technology
In the electronics and battery industries, NEP is used in the formulation of electrolytes for lithium-ion batteries. Electrolytes are crucial for the functioning of rechargeable batteries, and NEP helps improve their ionic conductivity, which in turn enhances the performance and longevity of these batteries. Lithium-ion batteries are widely used in consumer electronics like smartphones, laptops, and electric vehicles. By improving the electrolyte's conductivity, NEP contributes to increasing the efficiency and lifespan of these energy storage devices.
4. Agriculture
NEP is also used in the agricultural sector, where it serves as a solvent in the production of agrochemicals such as pesticides, herbicides, and fungicides. NEP helps dissolve the active ingredients in these chemicals, ensuring that they are well-distributed and effective when applied. Its ability to enhance the solubility and stability of these substances ensures that they are effective at controlling pests and diseases while being easier to apply.
Health and Safety Considerations
Like many industrial chemicals, NEP requires careful handling to minimize risks. While it is not classified as highly hazardous, it is still important to follow safety protocols to avoid health issues, especially when handling large quantities or in poorly ventilated areas.
Skin and Eye Contact: Prolonged or repeated exposure to NEP can cause skin irritation, and care should be taken to avoid direct skin contact. If contact occurs, wash the affected area thoroughly with soap and water.
Inhalation: Inhaling vapors of NEP can cause respiratory irritation. Adequate ventilation should always be used, particularly in enclosed spaces, and personal protective equipment (PPE) such as gloves, goggles, and respiratory protection should be worn if necessary.
Regulatory Oversight: NEP is not classified as a carcinogen or mutagen. However, regulatory agencies such as the U.S. Environmental Protection Agency (EPA) and the European Chemicals Agency (ECHA) monitor its use to ensure that it meets safety standards and that any potential risks to workers or the environment are minimized.
Environmental Impact
One of the advantages of NEP is that it is biodegradable, meaning it can break down naturally over time in the environment. However, like any chemical compound, NEP should still be handled responsibly to reduce its environmental footprint. Proper waste disposal methods must be followed, and companies must ensure that any discharges of NEP are within permissible environmental limits.
The environmental impact of NEP is still being studied, and ongoing research aims to better understand its long-term effects. Nonetheless, due to its biodegradability, it is considered less harmful to the environment compared to many other solvents and chemicals.
Conclusion
N-ethyl-2-pyrrolidone (CAS No. 35180-01-9) is a versatile and important compound used across several industries, including chemicals, pharmaceuticals, electronics, and agriculture. Its solvent properties make it an essential ingredient in the production of many products, from medications to batteries. However, like all industrial chemicals, it must be handled with caution to protect both human health and the environment.
By understanding its properties and applications, industries can continue to use NEP effectively while minimizing risks associated with its handling and disposal. Proper safety protocols and environmental responsibility are key to ensuring that the benefits of NEP are maximized without causing harm to people or the planet.
URL: For more information, visit connex pharma : CAS NO. 35180-01-9

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