Dosage Form And Route Of Administration Are Heavily Intertwined With Pharmaceutical Drug Delivery

By Author: Poojacmi
Total Articles: 9
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Controlled-release or modified-release formulations alter the rate and timing of drug release in order to achieve adequate or sustained drug concentrations. Dexedrine was the first controlled-release (CR) formulation developed in the 1950s. During this time, more drugs were formulated as CR, and transdermal patches were introduced to allow drugs to slowly absorb through the skin. Since then, a plethora of other CR products have been developed to account for the physiochemical properties of various drugs, such as depot injections for antipsychotics and sex hormones that require monthly dosing. Since the late 1990s, the majority of CR formulation Pharmaceutical Drug Delivery research has focused on using nanoparticles to reduce drug clearance.

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