Benefits Of Atomic Force Microscopy In Cell Biology Research

By Author: Park Systems
Total Articles: 16
Comment this article

Cell biology research is complex and broad with technologies constantly advancing and innovations being introduced to help with the understanding of molecular biochemistry and microstructure. Atomic Force Microscopes (AFM) is one of the most used tools to help illuminate elusive cell mechanics and improve understanding of cellular processes, that generate and respond to mechanical forces. Many can be assessed in vitro thanks to the rapid probing capabilities of the AFM, enabling biochemists to get reliable data of cell mechanics and interactions that they couldn't identify in the past.

Virologists that carry out cell biology research have been using AFM for years to observe the initial interactions between viral microbes and biological tissues, which is critical at understanding the initial phases of infection for viral strains, including the current coronavirus. This provides reliable data for medical and life science professionals in the public health sector. AFM succeeds where other probing techniques fail.

Most of the interest in cell biological research is in living cells. Biochemists simulate physiological ...
... conditions, growing tissue samples in culturing media and incubating them at varying temperatures. It is not easy to use conventional technologies to acquire accurate measurements. AFM is one of the most powerful tools for quantitatively imaging cells in culture, measuring the viscoelastic and elastic responses of cells when exposed to mechanical stress and drugs.

In virology, it is possible to functionalist the measuring probe with a specific viral strain that is being observed, based on the response of the cells. This is an emerging application of AFM with great research potential. Cell biology research relies on atomic force microscopy to measure the responses of cells in culture to mechanical stimulation, carrying out excellent precision with sub-nanometer levels of resolution.

Being able to measure the minutest mechanical response of cells can offer reliable information on cell stiffness and viscoelastic variations, essential for cell biologists researching cancerous cells. The changes in viscoelasticity and stiffness are biomarkers of cellular metastatic potential. Atomic force microscopes enable biochemists to record mechanotransduction of cells in near-physiological conditions, offering accurate measurements.

When it comes to conducting biochemistry research and cell research, you must purchase the right atomic force microscope for the job to ensure the best results. There are several products on the market, though they are not all created equal. To ensure accurate results you want to research to find the best AFM product with outstanding after-sales support to help you with the job.

Research the AFM companies looking for those that offer thousands of AFM products and software, along with a growing full-time team of experts who pay close attention to detail when developing and designing their AFM products to ensure you enjoy accurate test results at all times.

Never rely on the reviews you find on their website alone, always do your research, learning as much about the company and then making use of independent review sites and online forums to get honest feedback from other researchers and virologists, this way you can narrow down your shortlist.

Look for a global company with partners around the world. This way you are assured that support is never far away. Arrange to see the AFM working. Let the company carry out a demonstration for you, so you can ensure it will be the right match based on your specific research needs and goals.

About Us: Park Systems is a leading supplier of AFM systems. This well-established company provides its clients with years of knowledge and experience in the industry. They comprise a dedicated team of experienced professionals who focus on providing the highest level of service and support to their clients daily. Park Systems design their system with care and attention to detail. They are focus-driven and have built up a solid reputation on a global scale. The company has a global sales network providing thirty years of experience with over 1,000 AFM’s available. They are the fastest-growing AFM company with more than one hundred and twenty full-time employees. To find out more, visit https://www.parksystems.com.