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Stem Cell Therapy Todays Hope, Tomorrow's Reality

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By Author: Vaishnav Kumar
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Stem cells therapy has been acknowledged to be a new medical boon, and many of us want to hear about the latest advancements and discoveries in stem cells and the science of regenerative medicine. Myriad of degenerative conditions have been harassing the mankind, mainly due to unavailability of concrete treatment pattern in the conventional way of medicine. For that matter, scientists all over the world are trying to explore inherent mechanism that is forcing stem cells to repair and regenerate.

Stem cells are identified to be the naïve cells of our body, which are involved in defining the entire cellular system. Although, stem cells applications have been recently explored, since the year 1970’s blood stem cells are widely used to treat many blood related disorders, like leukemia, malignant diseases, etc. The treatment can now be categorized as approved therapy and is being beneficial to many patients, who have been suffering with variety of blood related disorders.

Further to which, scientists have diverted their attention from autologous to allogenic applications of stem cells. Since then, numbers of sources have been identified from human body, which can be processed for further isolation of stem cells, like skin stem cells, extra embryonic tissue stem cells, etc. Scientists could demonstrate growth of new skin cells, from isolated skin biopsy, which could eventually be developed into an entirely new sheet of cells to be applied directly on wounds. Although, this crude development could not be supported; as the new skin, that is being formed did not have supported structures, like oil glands, sweat glands, hair follicles, etc.

Recently, more emphasize is expressed in stem cells isolated and cultured from autologous tissues, like bone marrow and adipose tissues. Hematopoietic stem cells isolated from bone marrow can develop a niche suitable for cellular growth, multiplication and regeneration; whereas stromal cells are the cells, which are actually involved in differentiation of dead and/or damaged cells. Thus, scientists have come to the conclusion that no particular stem cell can promote specific activity, on the other hand, cocktail of cells are to be involved like stromal mesenchymal stem cells, hematopoietic stem cells and PRP to confirm an effective treatment outcome.

In the past decade or two, different applications of stem cells have been investigated and have been further studied for better treatment outcome. Although, it is still early to define the efficiency of stem cells, in the current scenario; these stem cells therapy have been exhibited to be having better functioning capacity and better adaptivity required for cellular differentiation. Accordingly, the leading areas of progress can be noted as macular degeneration, neurological conditions like Alzheimer’ disease, Autism, Cerebral Palsy, etc. Metabolic disorders like diabetes mellitus, liver disorders, etc. Moreover, it should as well be noted that various other clinical investigations are going on, to test specific drugs that have been manufacture to stimulate resident stem cells in patient’s body.
Widespread applications of stem cells have confirmed the treatment to be safe and feasible; although effectiveness and degree of cure is very individualistic, it cannot be statistically analyzed.

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