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Know More About Stem Cell Therapy For Autism And Cerebral Palsy Treatment In Mumbai

By Author: Nupur Jha
Total Articles: 43

ASD or Autism Spectrum Disorders are the Neuro-developmental disorders, which are rising at an alarming rate. One in every 166 of children today is diagnosed with mild to severe forms of ASD. Autism is the most common kind of ASD. The Neuro-physiological abnormalities and alterations caused by Autism are multiple in numbers. Out of all the effects of the disease, neural hypoperfusion and immune abnormalities are the most common ones. Immune deregulation is often exhibited in the form of Crohn’s disease and the graft-versus-host disease. A major cause of autism is Ischemia and neural hypoperfusion also. An inadequate blood supply to the brain results in damage or death of the brain cells.


Brain Hypoperfusion in Autism and Stem Cell Therapy


It is found that children with autism suffer from impaired CNS circulation. This is a cause of hypoxia, a condition that is characterized by a low amount of oxygen reaching the brain cells. Autism is characterized by hypoperfusion, and resultant hypoxia, in certain brain areas. These brain areas help in functions like social interaction, face recognition and comprehension of language. Fortunately, the hypoxia in autistic children is not related to the death of the brain, but only causes an alteration in functions. But hypoperfusion also causes abnormalities concerned with the metabolic functions of the body.


Stem cell therapy for autism augments perfusion (delivering of blood to cells and tissues), restores cellular functionality and also provides for metabolic clearance. Stem cell therapy also helps in regeneration of neurons and the entry of the progenitor cells, which also have regenerative properties. As stem cell therapy can reverse hypoxia, it can help in reversal of Autism symptoms. Stem cells help in angiogenesis or the formation of new blood vessels and hence increase blood supply to the affected brain areas.


Immune Deregulation and Stem Cell Therapy


The immune system and the entry system collaborate in numerous ways. Characteristics including self and non-self-recognition, memory, and specificity are shared by the systems. All immune organs are also innervated, and there is bi-directional information flow between the 2 systems.


T and B cells are found in the immune system. Autistic children are found to suffer from the abnormalities of these cells. Children affected by Autism are also affected by overproduction of the astrocytes (a kind of brain cell), and subsequently, the overproduction of certain inflammatory agents that cause brain abnormalities and neural malfunction.


Stem cell administration decreases inflammation. These cells can also shut down the auto-immune responses. The transplantation of the MSC or the Mesenchymal Stem Cells that are derived from the bone marrow secrete some factors (like TGF-b and IL-10) that have an inhibitory effect on the immune system.


Post stem cell therapy, a patient shows improvement in behavioral patterns, including reduction in repetitive and stereotypical motions, and lowering of hyperactivity.


Some of the marked improvements of stem cell therapy for Autism include:


1. Better eye contact


2. Reduction of all kinds of self-stimulatory behavior


3. Improvement in communication skills


4. Lesser repetition of behavior/motor mannerisms


5. Less aggression


6. Better social interactions


Analysis and deductive techniques are used to see the improvement stem cell therapy has brought to the brain areas. The CT scan conducted post stem cell therapy shows repairing of the damaged areas of the brain. Stem cells are today used for providing Autism and Cerebral Palsy treatment in Mumbai at leading health care institutions. For instance, NeuroGen Brain and Spine Institute (NGBSI) is a one-stop destination for the stem cell treatment of all kinds of neurological disorders.

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