123ArticleOnline Logo
Welcome to 123ArticleOnline.com!

ALL » General >> View Article

Know More About Thiamine Or Vitamin B1

By Expert Author: Abinash Mallick

hiamine or thiamin or vitamin B1, named as the "thio-vitamine" ("sulfur-containing vitamin") is a water-soluble vitamin of the B complex. First named aneurin for the detrimental neurological effects if not present in the diet, it was eventually assigned the generic descriptor name vitamin B1. Its phosphate derivatives are involved in many cellular processes. The best-characterized form is thiamine pyrophosphate (TPP), a coenzyme in the catabolism of sugars and amino acids. Thiamine is used in the biosynthesis of the neurotransmitter acetylcholine and gamma-aminobutyric acid (GABA). In yeast, TPP is also required in the first step of alcoholic fermentation.

All living organisms use thiamine, but it is synthesized only in bacteria, fungi, and plants. Animals must obtain it from their diet, and thus, for them, it is an essential nutrient. Insufficient intake in birds produces a characteristic polyneuritis. In mammals, deficiency results in Korsakoff's syndrome, optic neuropathy, and a disease called beriberi that affects the peripheral nervous system (polyneuritis) and/or the cardiovascular system. Thiamine deficiency has a potentially fatal outcome if it remains untreated.[1] In less severe cases, nonspecific signs include malaise, weight loss, irritability and confusion.[2] It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Thiamine is a colorless organosulfur compound with a chemical formula C12H17N4OS. Its structure consists of aminopyrimidine and a thiazole ring linked by a methylene bridge. The thiazole is substituted with methyl and hydroxyethyl side chains. Thiamine is soluble in water, methanol, and glycerol and practically insoluble in less polar organic solvents. It is stable at acidic pH, but is unstable in alkaline solutions.[1][4] Thiamine, which is a N-heterocyclic carbene, can be used in place of cyanide as a catalyst for benzoin condensation.[5][6] Thiamine is unstable to heat, but stable during frozen storage. It is unstable when exposed to ultraviolet light[4] and gamma irradiation.[7][8] Thiamine reacts strongly in Maillard-type reactions.

Thiamine is found in a wide variety of foods at low concentrations. Yeast, yeast extract, and pork are the most highly concentrated sources of thiamine.[citation needed] In general, cereal grains are the most important dietary sources of thiamine, by virtue of their ubiquity. Of these, whole grains contain more thiamine than refined grains, as thiamine is found mostly in the outer layers of the grain and in the germ (which are removed during the refining process). For example, 100 g of whole-wheat flour contains 0.55 mg of thiamine, while 100 g of white flour contains only 0.06 mg of thiamine. In the US, processed flour must be enriched with thiamine mononitrate (along with niacin, ferrous iron, riboflavin, and folic acid) to replace that lost in processing. In Australia, thiamine, folic acid, and iodised salt are added for the same reason.[12] A whole foods diet is therefore recommended for deficiency.

For more information please visit Vitamin B1

Total Views : 49Word Count Appx. : 475See All articles From Author

General Articles

1. The Importance And Use Of Solid Rivets In Industries
Author: Alpesh

2. Wie Man Ein Abendkleid Wählen Das Ist Die Richtige Für Sie
Author: dameo.de

3. Erin Scharf Hat Eine Romanze Mit Brautkleider Mekleid
Author: mekleid

4. Are You Ready For The Ride Of Your Life?
Author: Ackerley Bach

5. Thminers Release 2 New Cryptocurrency Miners
Author: 1888PressRelease

6. Elegant Prom Dresses Znu.com
Author: ZNUZNU

7. Change It Up: Sit Or Stand Easily With Adjustable Desks
Author: Jensen Karp

8. Tough Choice This Week As There Are A Madden 17 Lot Of Juicy Matchups.
Author: Tough choice this week as there are a Madden 17 lo

9. Car Hauling Hours Determined By Congress
Author: parveen kumar

10. 5 Factors To Consider When Looking For Taxi Services In Nottingham
Author: Nottscars

11. The Bank Of The West Classic
Author: Unknown Member

12. Digital Marketing – The Competitive Advantage
Author: Mario Sazos

13. Planetary Mixer Plays The Vital Role In Concrete Industry
Author: Planetary Mixer Plays the Vital Role in Concrete I

14. Analysis Of Main Parts Of Concrete Equipment
Author: Analysis of Main Parts of concrete equipment

15. Ensure The Normal Working Of Concrete Mixing Machine
Author: Ensure the Normal Working of concrete mixing machi

Login To Account
Login Email:
Forgot Password?
New User?
Sign Up Newsletter
Email Address: