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It's about the spread of a lethal virus that becomes a worldwide pandemic, killing thousands of people as it gains momentum, and defeating the best efforts of disease control experts to identify it. That could be the synopsis of some sensationalist potboiler, aiming for cheap shocks.

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Contagion is anything but: its story is alarmingly believable and it dwells on the science involved in combating such a virus. The film starts with a blank screen and the sound of a woman coughing. It's Gwyneth Paltrow, as an American businesswoman who returns to America on a long-haul flight from Hong Kong feeling ill, and swiftly becomes the first fatality. To the dismay of her husband (Matt Damon), her young son soon succumbs too.

As the virus spreads alarmingly, with no treatment protocol or vaccine, key players emerge. Laurence Fishburne, a calm rational executive ...
... at Atlanta's Centre for Disease Control, comes under immense public pressure.

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Kate Winslet is a courageous Epidemic Intelligence Service officer who goes out among the stricken, looking for clues about how the virus started. Parents need to know that this tense pre-apocalyptic thriller from Oscar-winner director Steven Soderbergh has mature themes including losing loved ones to a deadly disease and living in a constant state of fear that you might be its next victim. Matt Damon stars as a man whose wife (Gwyneth Paltrow) falls ill after returning home from a trip. In one scene, their young son sees his mother lying on the kitchen floor, unresponsive. Beginning with her case, the government moves quickly to find a treatment and/or a cure for the swift-moving virus. The subject matter doesn't rely on gore to tell the story, but the idea of a virus affecting the human race at a rapid rate is always a frightening possibility, and the characters' paranoia is likely to keep viewers on the edge of their seats.

A shrewd, unsensationalistic, non-visual effects-dependent global disaster melodrama, Contagion creates a credible picture of how the world might react (and, up to a point, has reacted) in the face of a rapidily spreading mystery disease for which no cure exists. Director Steven Soderbergh and screenwriter Scott Z. Burns create unease and simmering tension without going over the top into souped-up suspense or gross-out moments (with one possible exception), which will automatically lessen interest among the lowest-common-denominator crowd. But the fine cast, likely solid critical reaction and undeniable topicality position this as a robust B.O. performer for the early fall season. The Warner Bros. release world premiered Saturday night at the Venice Film Festival.

Spanning the planet but keeping his focus intimate, Soderbergh plausibly sets up a scenario in which everyday human contact—people touching themselves, others and ordinary objects—triggers an inter-continental plague that instantly transforms the way people relate to one another and throws governments and the relevant medical institutions into a panic. The immediate twin issues are how to combat the disease, whatever it is, and how to deal with a populace increasingly inflamed by rumors that, thanks to personal electronic communications, travel even faster than does the virus.
Despite such familiar devices as ticking-clock calendar postings--”Day 14,” “Day 131”--military checkposts, the president going underground and so on, the feeling here is far more realistic and science-based than artificially concocted. Notwithstanding the urgent struggles faced by the diverse group of characters, including those such as the regular Joe played by Matt Damon, the heart of the movie rests with the medical professionals played by Kate Winslet, Jennifer Ehle and Laurence Fishburne, individuals placed on the anvil of the crisis whose performance under pressure will likely tell the tale.